Main
Research
Topics

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+ 35

Years of experience

We develop both basic and applied research in three main fields of biomedical engineering

  • Biosignal Analysis

    We develop signal-processing and artificial-intelligence methods to acquire, improve and interpret biomedical recordings, with a particular focus on cardiovascular signals and personalized physiological monitoring.

    Conceptual grayscale illustration of cardiovascular biosignal measurement with a fingertip sensor

    Our work addresses ECG and optical pulse quality, wearable monitoring and sleep-apnea assessment. In atrial fibrillation, we extract and characterize atrial activity, study how arrhythmias begin and terminate, and identify markers associated with treatment response. These complementary approaches support research into patient stratification and clinical decision support, with attention to reproducibility, recording artifacts and generalization beyond the data used to develop each method.

    This line is headed by José J. Rieta. Explore our results, research projects and available services.

  • Energy-Based Therapies

    We study and develop therapeutic technologies that deliver energy to biological tissues, including radiofrequency, microwave, laser and ultrasound approaches. Our research connects computational modeling, experimental validation and clinical collaboration.

    Conceptual grayscale illustration of an ablation probe in a tissue-mimicking laboratory phantom

    We investigate how tissue properties, blood flow, electrode design and energy delivery determine treatment effects. Applications include controlling cardiac ablation lesions, protecting nearby tissues and developing devices for tumor ablation and blood-sparing surgery. Research on pancreatic transection and duct treatment links these engineering methods with emerging surgical applications. Across these areas, models and experiments help assess treatment strategies while distinguishing preclinical findings from clinical evidence.

    This line is led by Enrique Berjano. Explore our results, research projects and available services. You can learn more about this research line by visiting the metablate website.

  • Electroporation-Based Therapies

    We develop and assess therapies that use pulsed electric fields to alter cell-membrane permeability and target biological tissues. The line focuses on cardiac arrhythmias and cancer through computational modeling, experimental studies and clinical collaboration.

    Conceptual grayscale illustration of electrodes and a tissue-mimicking laboratory phantom

    Our research examines how anatomy, tissue composition, electrode geometry and pulse delivery shape the treated region. Cardiac applications include targeting autonomic ganglia and assessing interactions with coronary arteries and metallic stents. Tumor-treatment research explores electrode configurations and conductivity modification to improve treatment selectivity. Electrical and thermal effects are studied together to identify design constraints and safety questions, with emerging approaches assessed primarily through computational and preclinical evidence.

    This line is headed by Ana González-Suárez. Explore our research results, projects and services.